FHx (+): MI/angina/CABG/stent/angioplasty/sudden cardiac death in parent/grandparent/aunt/uncle: male <55, female <65.
High-level RFs
- Hypertension requiring drug therapy (BP ≥99th%ile + 5 mmHg)
- Current cigarette smoker
- BMI ≥97th%ile
- Presence of high-risk conditions (below)
Moderate-level RFs
- Hypertension not requiring drug therapy
- BMI ≥95th%ile and <97th%ile
- HDL-C <40 mg/dL
- Presence of moderate-risk conditions (below)
High-risk conditions
- Diabetes mellitus (Type 1 or Type 2)
- Homozygous familial hypercholesterolemia (hoFH)
- Chronic/end-stage renal disease or post-renal transplant
- Kawasaki disease with persistent coronary aneurysms/stenoses/occlusions
- Orthotopic heart transplantation
Moderate-risk conditions
- Familial hypercholesterolemia (FH)
- Kawasaki disease with regressed coronary aneurysms
- Chronic inflammatory disease (juvenile rheumatoid arthritis; SLE)
- HIV
- Nephrotic syndrome